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Vitamin B17: Busted Myths And Brutal Deaths!
Cancer. One disease that every person on this planet is most scared about. For centuries, the medical and research fields are doing all they can to prevent and cure cancers.
Pharmaceutical companies come up with vaccines, antibodies, drugs, and also gene-level therapies to fight the beast. Most approaches turn unsuccessful for various reasons. But every controversial approach has its share of benefits too.
Vitamin B17a.k.aLaetrileis one of those controversial anticancer drugs that took the pharma market by storm in the 1950s. Good or bad – it’s for the FDA and global markets to decide. But I’ve found some interesting facts and adverse effects of vitamin B17. Want to know more? Go ahead with your read!
Table Of Contents
What Is Vitamin B17?
Also called laetrile, vitamin B17 is a semi-synthetic derivative of amygdalin. Amygdalin (mandelonitrile beta-D-gentiobioside) is a chemical constituent of many fruits and numerous plants. Its synthetic version, laetrile, was first used as a cancer treatment in Russia in 1845.
It was introduced in the United States in the 1920s.
Laetrile stirred a huge controversy when US researchers found hydrogen cyanide to be the principal anticancer compound formed in laetrile. Eventually, laetrile use was banned for any cancer treatment in the US ().
Why am I not using the word vitamin B17? (You must have observed that by now.) Scroll down to know why!
Is Vitamin B17 Really A Vitamin?
No, it is not! In fact, there is no such element called vitamin B17.
Laetrile gained popularity in the 1970s as an anticancer agent. It was then termed ‘vitamin B 17’ by E.T. Krebs Jr. as a sales strategy. But it is not an approved designation by the Committee on Nomenclature of the American Institute of Nutrition Vitamins.
The chemical composition of U.S.-patented laetrile,a semi-synthetic derivative of amygdalin, is different from the laetrile/amygdalin produced in Mexico (mandelonitrile beta-D-gentiobioside),which is made from crushed apricot pits.
Although the names laetrile, vitamin B 17, and amygdalin are often used interchangeably,they are not the same product.
What Is Amygdalin?
- Amygdalinis a naturally occurring compound (cyanogenic glucoside) found in the pits of many fruits, nuts, and seeds; particularly in the plant families of Rosaceae, genusPrunus,Fabaceae, andPoaceae.
- Common sources of natural amygdalin areapricots, peaches, bitter almonds, flaxseeds, and millets.
- These plants have the enzymes (calledemulsin) required to break down amygdalin into benzaldehyde, glucose, and hydrocyanic acid.
- The enzymatic breakdown of amygdalin yields these products as adefense mechanismto the plants. Hence, amygdalin and its enzyme machinery are stored in thestony outer shellsand seeds of the fruits and nuts.
- Compartmentalizationof the toxic by-products will ensure the safety or viability of the fruit while killing the pest or pathogen.
Creepy much! To find out where amygdalin occurs in nature, continue reading.
What Are The Natural Sources Of Amygdalin?
Take a look at the list of foods fromRosaceaeand non-Rosaceaefamilies, and processed foods along with their amygdalin content in mg/g.Fruit seedsAmygdalin content
|Apricot||14.37 ± 0.28|
|Cherry (black)||2.68 ± 0.02|
|Cherry (red)||3.89 ± 0.31|
|Nectarine (summer fire)||0.12 ± 0.01|
|Peach||6.81 ± 0.02|
|Plum (green)||17.49 ± 0.26|
|Plum (black; friar black)||10.00 ± 0.14|
|Plum (yellow; son gold)||1.54 ± 0.02|
|Plum (purple; larry lane)||2.16 ± 0.02|
|Plum (red; laetitia)||0.44 ± 0.04|
|Apple (royal gala)||2.96 ± 0.02|
|Pear (conference)||1.29 ± 0.04|
|Courgette||0.21 ± 0.13|
|Cucumber||0.07 ± 0.02|
|Marrow||0.06 ± 0.01|
|Melon (honey dew)||0.12 ± 0.07|
|Squash (crown prince)||0.11 ± 0.22|
|Squash (acorn)||0.07 ± 0.03|
|Squash (red kabocha)||0.07 ± 0.11|
|Squash (butternut)||0.01 ± 0.04|
|Almond (toasted)||0.12 ± 0.06|
|Almond milk||0.05 ± 0.01|
|Almond cocoa desert||0.04 ± 0.02|
|Almond flour||0.03 ± 0.01|
|Apple juice (100% pressed)||0.09 ± 0.03|
|Apple and beetroot juice||0.02 ± 0.02|
|Apple puree||0.02 ± 0.01|
|Apricot slices tinned in juice||0.05 ± 0.07|
|Fruit smoothie (pasteurized)||0.01 ± 0.02|
|Peach drink||0.04 ± 0.05|
|Peach slices tinned in juice||0.06 ± 0.01|
|Prune slices tinned in juice||0.03 ± 0.03|
|Marzipan||0.02 ± 0.01|
It’s alarming to see high amygdalin levels inRosaceaefruits (). I was binging on them all this while! Also, check out the other dietary sources that contain high amygdalin levels below ():1. Beans2. Berries3. Grasses4. Grains5. Seeds6. Miscellaneous
I hope this compilation helps you choose the right dietary components.
What if one of the amygdalin-rich foods is your favorite? Or what if you are advised to consume such foods for some reason? I got that! Scroll down.
How Do You Consume Amygdalin-Rich Foods?
- You can have cyanogenic plants in different ways; some are often consumed without their seeds (apples, pears, apricots, berries, etc.).
- Some are usually consumed with their seeds (courgettes, cucumbers, almonds).
Despite the controversy and fatal chemical composition, most of us eat these foods. That’s because of the potential benefits they could have on your body. Take a look.
Can Amygdalin Or Laetrile-Rich Foods Benefit You? How?
Could Be Used To Cure Cancer
One of the biggest controversies in the Western world happened due to the use of laetrile to cure cancer.
Laetrile is the semi-synthetic variant of amygdalin. When administered to cancer patients, the cellular enzymes in the body broke down amygdalin to release hydrogen cyanide and benzaldehyde. According to hypothesis, the hydrogen cyanide would selectively kill the cancer cells while the patient stayed unharmed.
On the contrary, though the patients were cured (temporarily) of cancer, they later died of cyanide poisoning and related complications. Hence the controversy and thebanon laetrile and amygdalin ().
- Laetrile is an acronym for ‘laevorotatory and mandelonitrile.’Oral amygdalin is estimated to be40 times more potentthan its intravenous form due to its enzymatic conversion to hydrogen cyanide in the GI tract.
- 1–2 mg/kg is a fatal oral dose of cyanide for a person weighing 154 lbs (70 kg).
- It isillegalto use laetrile for treating cancer or any disorders. The US FDA hasnot approvedof its usage across the United States.
So, what can cyanide poisoning do? Does it have any signs? What are the risks associated with laetrile or amygdalin-rich foods? Here are some answers.
Fatal Side Effects Of Amygdalin Or Laetrile
In the name of curing cancer, if you don’t minimize your amygdalin exposure (and, consequently, exposure to hydrogen cyanide), you might face acute and sub-acute health problems like (),():
- Abdominal cramps
- Abnormally low blood pressure
- Red skin coloration
- Kidney failure
- Lactic acidosis
- Droopy upper eyelids
- Tissue necrosis (damage and death)
- Liver damage
- Loss of control and coordination
- Mental confusion
- Severe nerve damage
- Coma, and lastly
What’s The Verdict?
The benefit-to-risk ratio for laetrile or amygdalin is negative. Undoubtedly, looking at the side effects, it is lethal to take this vitamin B17 and amygdalin.
If somebody out there announces a new anticancer vitamin pill or a fancy chemo-free treatment, do not sign up. Double check the terminology used. Beware of misnomers as in the case of laetrile and vitamin B17.
While battling cancer, above strength and courage, what you’d need isawareness. You deserve the best of the treatments available, but not without your consent. If an oncologist prescribes a dozen pills, ask them what each one does.
Read about every medicine, its side effects, recommended dosage, etc., on FDA web pages, reputed forums, or even books. Be alert and aware of what’s going into your body.
Lastly, reduce the intake of amygdalin-rich foods, stay away from any pills in that come with the name of vitamin B17 or laetrile, make an informed decision at each step, and put up a tough fight. You can do it!
If this article blew your mind, gave you insights and strength you were seeking for, give us your feedback by commenting in the box below. We’d love to listen to your success stories too. Feel free to share your experiences and suggestions with us.
1. “” PubMed Health, US National Library of Medicine
2. “” Food Chemistry, Elsevier
3. “” eCOMMONS, Loyola University
4. “” Case Reports in Emergency Medicine, US National Library of Medicine
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