Real Cannabis Vs. Weed-simulations - Marinol or Sativex
What Is Marinol (Dronabinol)?
Marinol is the brand name for the prescription drug dronabinol. Doctors prescribe the drug to treat nausea and vomiting caused by chemotherapy when other treatments aren't effective. Doctors also prescribe Marinol to treat appetite and weight loss in people with AIDS.
Marinol is in a class of medications called cannabinoids, which impact the central nervous system. Dronabinol, the active ingredient in Marinol, is synthetic delta-9-tetrahydrocannabinol (THC), the psychoactive component of marijuana. Dronabinol affects the area of the brain responsible for appetite, nausea, and vomiting.
Banner Pharmacaps for AbbVie (formerly Unimed) developed the drug, and the Food and Drug Administration (FDA) first approved Marinol in 1985 to treat nausea and vomiting associated with cancer chemotherapy. In 1992, the FDA extended the approved uses of Marinol to include the treatment of weight loss in people with AIDS.
What Are the Key Things I Need to Know About Marinol?
Dronabinol may be habit-forming. It's important to take this medication exactly as your doctor prescribes it. Don't take more than you should at one time or take it more often than prescribed. Take Marinol with caution if you have a history of substance abuse.
Marinol can worsen certain mental illnesses, such as mania, depression, bipolar disorder or schizophrenia.
If you have a heart problem, taking Marinol could cause increased heart rate, decreased blood pressure, and fainting.
It's also important to understand that Marinol could alter your mood or cause feelings of being "high." For some people, these side effects can be troubling.
Read the complete FDA warning on Marinol.
Is There Anything Special I Should Discuss With My Doctor Before Taking Marinol?
Marinol may cause side effects and can interfere with many medications. If you have certain medical conditions, use Marinol (dronabinol) with caution. Always tell your doctor if you have allergies to any medication and discuss all the risks and benefits of the drug.
Before taking Marinol, let your doctor know if you have ever used marijuana or other illegal drugs. Also tell your doctor if you are or have ever been a heavy drinker.
Your doctor also needs to know if you've ever had any of the following:
- Heart disease
- High blood pressure
- A mental illness, such as mania (abnormally excited mood), depression, or schizophrenia (a mental disorder that causes disturbed or strange thinking as well as strong or inappropriate feelings)
Tell your doctor if you have any type of surgery planned, including dental surgery.
Your doctor should also know if you are pregnant, may become pregnant, or are breastfeeding. It’s unknown whether Marinol is safe to take during pregnancy. Nursing women shouldn't use the drug because it may pass into breast milk.
Although doctors don't prescribe Marinol for AIDS-related weight loss among children, young people may take it for nausea related to chemotherapy. Because of the effects of the drug on the brain, however, prescribing the drug for children requires extra caution.
Older people may also be more sensitive to the effects of Marinol. Experts recommend that doctors prescribe the drug for older people conservatively, at the lowest effective dose.
Marinol Side Effects
What Are the Most Common and Serious Side Effects of Marinol?
Common side effects of Marinol include:
- Sudden feeling of warmth
- Stomach pain
- Nausea or vomiting
- Memory loss
- Lack of balance
- Feeling like you are outside your body
- ''High'' or elevated mood
- Hallucinations (seeing things or hearing voices that do not exist)
- Strange or unusual thoughts
Serious side effects can also occur. If you have any of these side effects, stop taking dronabinol and call your doctor right away:
- Fast or pounding heartbeat
Because dronabinol may be habit-forming, stopping it abruptly may cause withdrawal symptoms, such as:
- Trouble sleeping
- Hot flashes
- Runny nose
- Loss of appetite
Do Other Drugs Affect the Way Marinol Works?
Many drugs may affect the way Marinol works, and Marinol may affect other medications. It's very important to let your doctor know about everything you are taking, including street drugs and any over-the-counter herbs or supplements.
Types of drugs that interact with Marinol (dronabinol) include:
Should I Avoid Any Food, Drink, or Activity While Taking Marinol?
It's important to understand that dronabinol may make you feel drowsy. It could also cause you to experience changes in your mood, thinking, judgment, and memory. This may be particularly evident when you first start your treatment. When you begin taking the drug and whenever your doctor increases your dose, it helps to have a responsible adult monitor you.
While taking Marinol, don't drive, operate machinery, or do anything that requires you to be mentally alert. If you get up too quickly after sitting or lying down, you may become dizzy or lightheaded. Also, don't drink while you are on this medication because alcohol can worsen the side effects of the drug.
What Is a Typical Dose of Marinol?
Marinol comes in the form of soft gelatin capsules that you take by mouth. The capsules come in three different strengths: 2.5 milligrams (mg), 5 mg, and 10 mg.
The right dose for you depends on your condition and how you respond to the medication. Your doctor will likely start you on a low dose and may gradually increase it. If you develop side effects that do not go away in a few days, your doctor may reduce your dose.
When you take Marinol to treat nausea and vomiting caused by chemotherapy, you'll usually take a dose one to three hours before chemotherapy. You can also take it two to four hours after chemotherapy. The maximum doesn't typically exceed six daily doses.
If you use Marinol to boost your appetite, you'll usually take it twice a day before lunch and dinner or once before bedtime. Swallow capsules whole. Don't crush them in any way or chew them.
What Happens If I Take Too Much Marinol and Overdose?
It's important to take Marinol exactly as your doctor prescribed. Taking too much can cause a number of side effects. Symptoms of a Marinol overdose may include:
- Inappropriate happiness
- Sharper senses than usual
- Changed awareness of time
- Red eyes
- Fast heartbeat
- Memory problems
- Feeling that you are outside of your body
- Mood changes
- Trouble urinating
- Loss of coordination
- Extreme tiredness
- Difficulty speaking clearly
- Dizziness or fainting when standing up too fast
If you or someone else has symptoms of an overdose, call your local poison control center at 1-800-222-1222. If someone collapses or isn't breathing, call 911.
What Happens If I Miss a Dose of Marinol or Don't Take It as Prescribed?
Don't stop taking Marinol without talking with your doctor first. If you accidentally miss a dose, take it as soon as you remember it. If it's almost time for your next regular dose, however, skip the missed dose. Don't take twice as much at one time to make up for a missed dose.
Video: US GOVERNMENT MARIJUANA-TOP SECRET-MARINOL
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